14-3-3 eta anticorps (N-Term)

N° du produit ABIN2792143

Il existe 1 publication pour ce produit. L’anticorps anti-14-3-3 eta Polyclonal Lapin est utilisé pour la détection de 14-3-3 eta dans des échantillons de Humain, Lapin, Chien et Poisson zèbre (Danio rerio). Il a été validé pour WB et IHC.

Aperçu rapide pour 14-3-3 eta anticorps (N-Term) (ABIN2792143)

Antigène: 14-3-3 eta (YWHAH)

Reactivité: Humain, Lapin, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp 14-3-3 eta est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-14-3-3 eta anticorps

Épitope: N-Term

Fonction: YWHAH Antibody - N-terminal region

Séquence: ADGNEKKLEK VKAYREKIEK ELETVCNDVL SLLDKFLIKN CNDFQYESKV

Homologie: Dog: 100%, Human: 100%, Rabbit: 100%, Zebrafish: 78%

Attributs du produit: This is a rabbit polyclonal antibody against YWHAH. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human YWHAH

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-14-3-3 eta (ABIN2792143)

Ubl, Berg, Holzmann, Krüger, Berger, Arzberger, Bornemann, Riess: "14-3-3 protein is a component of Lewy bodies in Parkinson's disease-mutation analysis and association studies of 14-3-3 eta." dans: Brain research. Molecular brain research, Vol. 108, Issue 1-2, pp. 33-9, (2002) (PubMed).

Détails sur 14-3-3 eta

Antigène: 14-3-3 eta (YWHAH)

Autre désignation: YWHAH

Sujet:

Background Information: The YWHAH gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99 % identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide

Alternative Symbols: YWHA1

Protein Name: 14-3-3 protein eta

Poids moléculaire: 28kDa

ID gène: 7533

NCBI Accession: NP_003396

UniProt: Q04917

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, C21-Steroid Hormone Metabolic Process, Myometrial Relaxation and Contraction