Cyclin G2 anticorps (N-Term)
Aperçu rapide pour Cyclin G2 anticorps (N-Term) (ABIN2792163)
Antigène
Voir toutes Cyclin G2 (CCNG2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- MKDLGAEHLA GHEGVQLLGL LNVYLEQEER FQPREKGLSL IEATPENDNT
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Homologie
- Cow: 91%, Dog: 91%, Human: 100%, Mouse: 83%, Rat: 83%
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Attributs du produit
- This is a rabbit polyclonal antibody against CCNG2. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Protein A purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human CCNG2
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 344 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Cyclin G2 (CCNG2)
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Autre désignation
- CCNG2
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Sujet
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The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved among mammals. The nucleotide sequence of cyclin G1 and cyclin G2 are 53 % identical. Unlike cyclin G1, cyclin G2 contains a C-terminal PEST protein destabilization motif, suggesting that cyclin G2 expression is tightly regulated through the cell cycle.
Protein Interaction Partner: EFHC2, FAM208B, NRIP2, UBC, SKP2, SKP1, PPP2CA, PPP2R4, PPP2R5C, PPP2R5B,
Protein Size: 344 -
Poids moléculaire
- 39 kDa
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ID gène
- 901
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NCBI Accession
- NM_004354, NP_004345
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UniProt
- Q16589
Antigène
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