CXCR6 anticorps (N-Term)

N° du produit ABIN2792195

Détail du produit anti-CXCR6 anticorps

Antigène: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCR6 est non-conjugé

Application: Western Blotting (WB)

Séquence: AEHDYHEDYG FSSFNDSSQE EHQDFLQFSK VFLPCMYLVV FVCGLVGNSL

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CXCR6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CXCR6

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 342 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CXCR6

Antigène: CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))

Autre désignation: CXCR6 (CXCR6 Produits)

Synonymes: anticorps BONZO, anticorps CD186, anticorps STRL33, anticorps TYMSTR, anticorps BB217514, anticorps C-X-C motif chemokine receptor 6, anticorps chemokine (C-X-C motif) receptor 6 L homeolog, anticorps chemokine (C-X-C motif) receptor 6, anticorps CXCR6, anticorps cxcr6.L, anticorps Cxcr6

Sujet: CXCR6 is a receptor for the C-X-C chemokine CXCL16. It is used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.The CXCR6/AKT/mTOR pathway plays a central role in the development of prostate cancer. CXCR6 and CXCR3 act coordinately with respective ligands and are involved in the pathophysiology of Juvenile Idiopathic Arthritis-associated inflammatory processes. The CXCL16-CXCR6-system express in human schwannomas of different localization and in malignant peripheral nerve sheath tumors. The protein may play an important role in the retention of T cells within the lung.
Alias Symbols: BONZO, CD186, STRL33, TYMSTR
Protein Interaction Partner: CXCL16,
Protein Size: 342

Poids moléculaire: 39 kDa

ID gène: 10663

NCBI Accession: NM_006564, NP_006555

UniProt: O00574