CCL18 anticorps (Middle Region)

N° du produit ABIN2792202

Détail du produit anti-CCL18 anticorps

Antigène: CCL18 (Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCL18 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: PQKFIVDYSE TSPQCPKPGV ILLTKRGRQI CADPNKKWVQ KYISDLKLNA

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CCL18. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CCL18

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 89 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CCL18 (ABIN2792202)

Schraufstatter, Takamori, Sikora, Sriramarao, DiScipio: "Eosinophils and monocytes produce pulmonary and activation-regulated chemokine, which activates cultured monocytes/macrophages." dans: American journal of physiology. Lung cellular and molecular physiology, Vol. 286, Issue 3, pp. L494-501, (2004) (PubMed).

Détails sur CCL18

Antigène: CCL18 (Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))

Autre désignation: CCL18 (CCL18 Produits)

Synonymes: anticorps H7AP1, anticorps PARC, anticorps RP3-330M21.2, anticorps AMAC-1, anticorps AMAC1, anticorps CKb7, anticorps DC-CK1, anticorps DCCK1, anticorps MIP-4, anticorps SCYA18, anticorps cullin 9, anticorps C-C motif chemokine ligand 18, anticorps CUL9, anticorps CCL18

Sujet: CCL18 is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by CCL18 displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses.
Alias Symbols: CKb7, PARC, AMAC1, DCCK1, MIP-4, AMAC-1, DC-CK1, SCYA18
Protein Interaction Partner: C14orf1, UNC119, CRMP1, TLE1, TP53, EEF1A1,
Protein Size: 89

Poids moléculaire: 10 kDa

ID gène: 6362

NCBI Accession: NM_002988, NP_002979

UniProt: P55774