FFAR1 anticorps (N-Term)

N° du produit ABIN2792205

Détail du produit anti-FFAR1 anticorps

Antigène: FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Porc, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FFAR1 est non-conjugé

Application: Western Blotting (WB)

Séquence: KVSEAALSLL VLILIITSAS RSQPKVPEWV NTPSTCCLKY YEKVLPRRLV

Homologie: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 85%, Pig: 92%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against FFAR1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human FFAR1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 300 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-FFAR1 (ABIN2792205)

Sum, Tikhonova, Neumann, Engel, Raaka, Costanzi, Gershengorn: "Identification of residues important for agonist recognition and activation in GPR40." dans: The Journal of biological chemistry, Vol. 282, Issue 40, pp. 29248-55, (2007) (PubMed).

Détails sur FFAR1

Antigène: FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))

Autre désignation: FFAR1 (FFAR1 Produits)

Synonymes: anticorps FFAR1, anticorps GPR40, anticorps FFA1R, anticorps GPCR40, anticorps Gpr40, anticorps free fatty acid receptor 1, anticorps FFAR1, anticorps Ffar1

Sujet: FFAR1 is receptor for medium and long chain saturated and unsaturated fatty acids. It binding of the ligand increase intracellular calcium concentration and amplify glucose-stimulated insulin secretion. The activity of this receptor is mediated by G-proteins that activate phospholipase C.
Alias Symbols: FFA1R, GPCR40, GPR40
Protein Interaction Partner: GNAQ, GNAI1,
Protein Size: 300

Poids moléculaire: 31 kDa

ID gène: 2864

NCBI Accession: NM_005303, NP_005294

UniProt: O14842

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Carbohydrate Homeostasis