TRAF4 anticorps (Middle Region)

N° du produit ABIN2792211

Cet anticorps anti-TRAF4 est un anticorps Lapin Polyclonal détectant TRAF4 dans WB. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval et Poisson zèbre (Danio rerio).

Aperçu rapide pour TRAF4 anticorps (Middle Region) (ABIN2792211)

Antigène: TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRAF4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TRAF4 anticorps

Épitope: Middle Region

Séquence: LEAPGGWLDH SNTSLGINTP VNGSPVCLEA WDPASAGPAR FSLSLLLFFL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TRAF4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TRAF4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 470 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TRAF4

Antigène: TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))

Autre désignation: TRAF4

Sujet: TRAF4 is a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. It has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK.This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CART1, MLN62, RNF83
Protein Interaction Partner: HOMEZ, BYSL, REXO1L6P, PKD1P1, KANSL1, BCL6B, UBL4B, KRT40, FBXL18, BANP, SPDL1, ALKBH4, WBP11, ZNF581, ISYNA1, TBC1D7, GORASP2, EXOC7, BAHD1, WWP2, WWP1, MRPL28, NOS1AP, TRAF4, UBL4A, ZNF3, SUMO1, UBC, TYK2, TP53BP2, QARS, KRT31, ARNT2, TRAF2, USP15, TGF
Protein Size: 470

Poids moléculaire: 53 kDa

ID gène: 9618

NCBI Accession: NM_004295, NP_004286

UniProt: Q9BUZ4