Caveolin 3 anticorps (N-Term)

N° du produit ABIN2792221

Cet anticorps Lapin Polyclonal détecte spécifiquement Caveolin 3 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Porc et Boeuf (Vache).

Aperçu rapide pour Caveolin 3 anticorps (N-Term) (ABIN2792221)

Antigène: Caveolin 3 (CAV3)

Reactivité: Humain, Souris, Rat, Porc, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caveolin 3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Caveolin 3 anticorps

Épitope: N-Term

Fonction: CAV3 Antibody - N-terminal region

Séquence: MMAEEHTDLE AQIVKDIHCK EIDLVNRDPK NINEDIVKVD FEDVIAEPVG

Homologie: Cow: 100%, Human: 100%, Mouse: 84%, Pig: 92%, Rat: 84%

Attributs du produit: This is a rabbit polyclonal antibody against CAV3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CAV3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Caveolin 3

Antigène: Caveolin 3 (CAV3)

Autre désignation: CAV3

Sujet:

Background Information: CAV3 is a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.

Gene Name: Caveolin 3

Alternative Symbols: LQT9, MPDT, RMD2, VIP21, LGMD1C, VIP-21

Protein Name: Caveolin-3

Poids moléculaire: 17kDa

ID gène: 859

NCBI Accession: NP_001225

UniProt: P56539

Pathways: Carbohydrate Homeostasis, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity