DOK2 anticorps (C-Term)

N° du produit ABIN2792223

Cet anticorps anti-DOK2 est un anticorps Lapin Polyclonal détectant DOK2 dans WB. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Chien, Porc et Cheval.

Aperçu rapide pour DOK2 anticorps (C-Term) (ABIN2792223)

Antigène: DOK2

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOK2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DOK2 anticorps

Épitope: C-Term

Séquence: QEPRGEAWRR QATRDRDPAG LQHVQPAGQD FSASGWQPGT EYDNVVLKKG

Homologie: Cow: 100%, Dog: 90%, Horse: 90%, Human: 100%, Mouse: 90%, Pig: 100%, Rat: 90%

Attributs du produit: This is a rabbit polyclonal antibody against DOK2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human DOK2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 412 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DOK2

Antigène: DOK2

Autre désignation: DOK2

Sujet: DOK2 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. DOK2 binds p120 (RasGAP) from CML cells.The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.
Alias Symbols: p56DOK, p56dok-2
Protein Interaction Partner: UBC, RASA1, ABL1, POT1, EGFR, KIAA1279, INPP5D, NCK1, TEK, SRC, LYN, RET, LCK, IL4R, HCK, HSPA4L, ASF1B, DNAJB11, RAB10, SSSCA1, CFLAR, SPOP, SHC1, PSMD10, DOK1,
Protein Size: 412

Poids moléculaire: 45 kDa

ID gène: 9046

NCBI Accession: NM_003974, NP_003965

UniProt: O60496