DOK2 anticorps (C-Term)

N° du produit ABIN2792223

Cet anticorps anti-DOK2 Polyclonal Lapin (ABIN2792223) détecte spécifiquement DOK2 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Porc et Cheval.

Aperçu rapide pour DOK2 anticorps (C-Term) (ABIN2792223)

Antigène: DOK2

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOK2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DOK2 anticorps

Épitope: C-Term

Fonction: DOK2 Antibody - C-terminal region

Séquence: QEPRGEAWRR QATRDRDPAG LQHVQPAGQD FSASGWQPGT EYDNVVLKKG

Homologie: Cow: 100%, Dog: 90%, Horse: 90%, Human: 100%, Mouse: 90%, Pig: 100%, Rat: 90%

Attributs du produit: This is a rabbit polyclonal antibody against DOK2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human DOK2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur DOK2

Antigène: DOK2

Autre désignation: DOK2

Sujet:

Background Information: DOK2 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. DOK2 binds p120 (RasGAP) from CML cells.The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.

Gene Name: Docking protein 2, 56 kDa

Alternative Symbols: p56DOK, p56dok-2

Protein Name: Docking protein 2

Poids moléculaire: 45kDa

ID gène: 9046

NCBI Accession: NP_003965

UniProt: O60496