PDCD4 anticorps (N-Term)

N° du produit ABIN2792230

Il existe 2+ publications pour ce produit. L’anticorps anti-PDCD4 Polyclonal Lapin est utilisé pour la détection de PDCD4 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Chévre et Cobaye. Il a été validé pour WB.

Aperçu rapide pour PDCD4 anticorps (N-Term) (ABIN2792230)

Antigène: PDCD4 (Programmed Cell Death 4 (PDCD4))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Chévre, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDCD4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PDCD4 anticorps

Épitope: N-Term

Fonction: PDCD4 Antibody - N-terminal region

Séquence: MTKYPDNLSD SLFSGDEENA GTEEIKNEIN GNWISASSIN EARINAKAKR

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PDCD4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PDCD4

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-PDCD4 (ABIN2792230)

Pan, Luo, Chegini: "microRNA 21: response to hormonal therapies and regulatory function in leiomyoma, transformed leiomyoma and leiomyosarcoma cells." dans: Molecular human reproduction, Vol. 16, Issue 3, pp. 215-27, (2010) (PubMed).

Folini, Gandellini, Longoni, Profumo, Callari, Pennati, Colecchia, Supino, Veneroni, Salvioni, Valdagni, Daidone, Zaffaroni: "miR-21: an oncomir on strike in prostate cancer." dans: Molecular cancer, Vol. 9, pp. 12, (2010) (PubMed).

Détails sur PDCD4

Antigène: PDCD4 (Programmed Cell Death 4 (PDCD4))

Autre désignation: PDCD4

Sujet:

Background Information: PDCD4 is a protein localized to the nucleus in proliferating cells. Expression of its gene is modulated by cytokines in natural killer and T cells. PDCD4 is thought to play a role in apoptosis but the specific role has not yet been determined.This gene encodes a protein localized to the nucleus in proliferating cells. Expression of this gene is modulated by cytokines in natural killer and T cells. The gene product is thought to play a role in apoptosis but the specific role has not yet been determined. Two transcripts encoding different isoforms have been identified.

Gene Name: Programmed cell death 4 (neoplastic transformation inhibitor)

Alternative Symbols: H731

Protein Name: Programmed cell death protein 4

Poids moléculaire: 50kDa

ID gène: 27250

NCBI Accession: NP_663314

UniProt: Q53EL6