BCL2A1 anticorps (C-Term)
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- Antigène Voir toutes BCL2A1 Anticorps
- BCL2A1 (BCL2-Related Protein A1 (BCL2A1))
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Épitope
- C-Term
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Reactivité
- Rat, Porc, Chien
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp BCL2A1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- FIMNNTGEWI RQNGGWENGF VKKFEPKSGW MTFLEVTGKI CEMLSLLKQY
- Homologie
- Dog: 90%, Pig: 85%, Rat: 78%
- Attributs du produit
- This is a rabbit polyclonal antibody against BCL2A1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human BCL2A1
- Top Product
- Discover our top product BCL2A1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 175 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- BCL2A1 (BCL2-Related Protein A1 (BCL2A1))
- Autre désignation
- BCL2A1 (BCL2A1 Produits)
- Synonymes
- anticorps ACC-1, anticorps ACC-2, anticorps BCL2L5, anticorps BFL1, anticorps GRS, anticorps HBPA1, anticorps Bcl2a1d, anticorps BCL2A1, anticorps BCL2 related protein A1, anticorps BCL2-related protein A1, anticorps BCL2A1, anticorps Bcl2a1
- Sujet
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BCL2A1s a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival.
Alias Symbols: GRS, BFL1, ACC-1, ACC-2, HBPA1, BCL2L5
Protein Interaction Partner: FAM9B, NR4A1, BIK, BAK1, APP, HAT1, BBC3, PMAIP1, BOK, BCL2L11, HRK, BAD, BID, BAX, GRB2, BMF,
Protein Size: 175 - Poids moléculaire
- 20 kDa
- ID gène
- 597
- NCBI Accession
- NM_004049, NP_004040
- UniProt
- Q16548
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