BCL2A1 anticorps (C-Term)

N° du produit ABIN2792231

Cet anticorps anti-BCL2A1 Polyclonal Lapin (ABIN2792231) détecte spécifiquement BCL2A1 dans WB. L’anticorps est réactif avec des échantillons de Rat, Porc et Chien.

Aperçu rapide pour BCL2A1 anticorps (C-Term) (ABIN2792231)

Antigène: BCL2A1 (BCL2-Related Protein A1 (BCL2A1))

Reactivité: Rat, Porc, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCL2A1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BCL2A1 anticorps

Épitope: C-Term

Fonction: BCL2A1 Antibody - C-terminal region

Séquence: FIMNNTGEWI RQNGGWENGF VKKFEPKSGW MTFLEVTGKI CEMLSLLKQY

Homologie: Dog: 90%, Pig: 85%, Rat: 78%

Attributs du produit: This is a rabbit polyclonal antibody against BCL2A1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human BCL2A1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur BCL2A1

Antigène: BCL2A1 (BCL2-Related Protein A1 (BCL2A1))

Autre désignation: BCL2A1

Sujet:

Background Information: BCL2A1s a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and has been shown to be up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival.

Gene Name: BCL2-related protein A1

Alternative Symbols: GRS, ACC1, ACC2, BFL1, ACC-1, ACC-2, HBPA1, BCL2L5

Protein Name: Bcl-2-related protein A1

Poids moléculaire: 20kDa

ID gène: 597

NCBI Accession: NP_004040

UniProt: Q16548