Serotonin Receptor 3A anticorps (N-Term)

N° du produit ABIN2792275

Il existe 1 publication pour ce produit. L’anticorps anti-Serotonin Receptor 3A Polyclonal Lapin est utilisé pour la détection de Serotonin Receptor 3A dans des échantillons de Humain, Rat, Souris, Chien, Boeuf (Vache) et Cheval. Il a été validé pour WB et IHC.

Aperçu rapide pour Serotonin Receptor 3A anticorps (N-Term) (ABIN2792275)

Antigène: Serotonin Receptor 3A (HTR3A)

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Serotonin Receptor 3A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Serotonin Receptor 3A anticorps

Épitope: N-Term

Fonction: HTR3A Antibody - N-terminal region

Séquence: LLLPTLLAQG EARRSRNTTR PALLRLSDYL LTNYRKGVRP VRDWRKPTTV

Homologie: Cow: 78%, Dog: 78%, Horse: 91%, Human: 100%, Mouse: 78%, Rat: 78%

Attributs du produit: This is a rabbit polyclonal antibody against HTR3A. It was validated on Western Blot using a cell lysate as a positive control.

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human HTR3A

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Serotonin Receptor 3A (ABIN2792275)

Rinaldi, Chiaravalli, Mian, Zucca, Tibiletti, Capella, Bertoni: "Serotonin receptor 3A expression in normal and neoplastic B cells." dans: Pathobiology : journal of immunopathology, molecular and cellular biology, Vol. 77, Issue 3, pp. 129-35, (2010) (PubMed).

Détails sur Serotonin Receptor 3A

Antigène: Serotonin Receptor 3A (HTR3A)

Autre désignation: HTR3A

Sujet:

Background Information: HTR3A belongs to the ligand-gated ion channel receptor superfamily. It is the subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Name: 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

Alternative Symbols: HTR3, 5HT3R, 5-HT-3, 5-HT3A, 5-HT3R

Protein Name: 5-hydroxytryptamine receptor 3A

Poids moléculaire: 55 kDa

ID gène: 3359

NCBI Accession: NP_000860

UniProt: P46098

Pathways: Synaptic Membrane