STX1A anticorps (N-Term)

N° du produit ABIN2792295

Détail du produit anti-STX1A anticorps

Antigène: STX1A (Syntaxin 1A (Brain) (STX1A))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STX1A est non-conjugé

Application: Western Blotting (WB)

Séquence: KDRTQELRTA KDSDDDDDVA VTVDRDRFMD EFFEQVEEIR GFIDKIAENV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against STX1A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human STX1A

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 288 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur STX1A

Antigène: STX1A (Syntaxin 1A (Brain) (STX1A))

Autre désignation: STX1A (STX1A Produits)

Synonymes: anticorps HPC-1, anticorps P35-1, anticorps STX1, anticorps SYN1A, anticorps STX1A, anticorps hpc-1, anticorps p35-1, anticorps stx1, anticorps sx1a, anticorps syntaxin1a, anticorps CG10716, anticorps CG18615, anticorps CG31136, anticorps CG5448, anticorps CT30033, anticorps Dm Syx1, anticorps DmSyx1A, anticorps Dmel\\CG31136, anticorps SYX1A, anticorps Syt1A, anticorps Syx, anticorps Syx-1A, anticorps Syx1, anticorps Syx1a, anticorps SyxA, anticorps anon-EST:Gibbs4, anticorps anon-WO02059370.54, anticorps dSyx1, anticorps l(3)06737, anticorps synt, anticorps syt-1A, anticorps syx, anticorps syx-1, anticorps syx-1A, anticorps syx1, anticorps syx1A, anticorps syntaxin 1A, anticorps syntaxin 1A (brain), anticorps Syntaxin 1A, anticorps syntaxin-1A, anticorps STX1A, anticorps Stx1a, anticorps stx1a, anticorps Syx1A, anticorps EDI_005240, anticorps Tsp_07354

Sujet: Synaptic vesicles store neurotransmitters that are released during calcium-regulated exocytosis. The specificity of neurotransmitter release requires the localization of both synaptic vesicles and calcium channels to the presynaptic active zone. Syntaxins function in this vesicle fusion process. Syntaxins also serve as a substrate for botulinum neurotoxin type C, a metalloprotease that blocks exocytosis and has high affinity for a molecular complex that includes the alpha-latrotoxin receptor which produces explosive exocytosis. Synaptic vesicles store neurotransmitters that are released during calcium-regulated exocytosis. The specificity of neurotransmitter release requires the localization of both synaptic vesicles and calcium channels to the presynaptic active zone. Syntaxins function in this vesicle fusion process. Syntaxins also serve as a substrate for botulinum neurotoxin type C, a metalloprotease that blocks exocytosis and has high affinity for a molecular complex that includes the alpha-latrotoxin receptor (MIM 600565) which produces explosive exocytosis (Zhang et al., 1995 [PubMed 7622072]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1253 BC064644.1 1-1253 1254-2117 BC000444.2 1209-2072
Alias Symbols: HPC-1, STX1, p35-1, P35-1, SYN1A
Protein Interaction Partner: STXBP1, SUMO1P1, TXLNA, TXLNB, NAPB, VAMP5, SNAP29, VAPB, SNAP23, STX1A, PSMA3, KCNB1, Htt, SNAP25, SLC6A3, SLC6A2, PPP1CA, pnut, Sep1, SNPH, TRDMT1, CCSER2, VPS11, SYT7, VPS18, RIMS1, CPLX1, SLC6A5, STXBP5, SYTL4, STXBP6, UNC13B, STX8, RAB27A, NAPA, VAMP
Protein Size: 288

Poids moléculaire: 33 kDa

ID gène: 6804

NCBI Accession: NM_004603, NP_004594

UniProt: Q16623

Pathways: Peptide Hormone Metabolism, Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport