STXBP1 anticorps (Middle Region)

N° du produit ABIN2792301

Détail du produit anti-STXBP1 anticorps

Antigène: STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

Épitope: Middle Region

Reactivité: Humain, Boeuf (Vache), Chien, Lapin, Poisson zèbre (Danio rerio), Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STXBP1 est non-conjugé

Application: Western Blotting (WB)

Séquence: TRSSASFSTT AVSARYGHWH KNKAPGEYRS GPRLIIFILG GVSLNEMRCA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against STXBP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human STXBP1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 594 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur STXBP1

Antigène: STXBP1 (Syntaxin Binding Protein 1 (STXBP1))

Autre désignation: STXBP1 (STXBP1 Produits)

Synonymes: anticorps MUNC18-1, anticorps NSEC1, anticorps P67, anticorps RBSEC1, anticorps UNC18, anticorps AI317162, anticorps AI326233, anticorps MMS10-G, anticorps Ms10g, anticorps Munc-18a, anticorps Munc18-1, anticorps N-sec1, anticorps Rb-sec1, anticorps Sxtbp1, anticorps Unc18-1, anticorps Unc18h, anticorps nsec1, anticorps fj43h10, anticorps stxbp1, anticorps wu:fj36d12, anticorps wu:fj43h10, anticorps zgc:114171, anticorps rop, anticorps unc18, anticorps hunc18, anticorps rbsec1, anticorps munc18-1, anticorps MGC146482, anticorps ANC18HA, anticorps NSEC1A, anticorps Sec1, anticorps n-sec1, anticorps nSec1, anticorps rbSec1, anticorps rbSec1A, anticorps rbSec1B, anticorps UNC18A, anticorps si:rp71-10d23.3, anticorps syntaxin binding protein 1, anticorps syntaxin binding protein 1a, anticorps syntaxin binding protein 1 L homeolog, anticorps syntaxin binding protein 1b, anticorps STXBP1, anticorps Stxbp1, anticorps stxbp1a, anticorps stxbp1, anticorps Tb09.160.0780, anticorps stxbp1.L, anticorps stxbp1b

Sujet: STXBP1 belongs to the STXBP/unc-18/SEC1 family. It may participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. The protein is essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. It can interact with syntaxins 1, 2, and 3 but not syntaxin 4.
Alias Symbols: MUNC18-1, UNC18, hUNC18, rbSec1, P67, NSEC1, RBSEC1
Protein Interaction Partner: STX19, SYTL4, TRIM38, STX11, STX1A, APBA2, APBA1, UBC, SQSTM1, DYT10, IQCB1, Htt, KCTD3, APP, STX3, STX2, USO1, DOC2B, DOC2A, CDK5R1, PLD2, PLD1, STX1B, PRKCG, PRKCB, PRKCA, NEFM, NEFH, MAPT, CDK5, HGS, Stx5, Dlg4, STX4, TUBB2A, TUBA4A,
Protein Size: 594

Poids moléculaire: 67 kDa

ID gène: 6812

NCBI Accession: NM_001032221, NP_001027392

UniProt: P61764

Pathways: Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport