DEK anticorps (N-Term)

N° du produit ABIN2792543

Il existe 1 publication pour ce produit. L’anticorps anti-DEK Polyclonal Lapin est utilisé pour la détection de DEK dans des échantillons de Humain, Rat, Boeuf (Vache), Lapin, Cobaye et Cheval. Il a été validé pour WB.

Aperçu rapide pour DEK anticorps (N-Term) (ABIN2792543)

Antigène: DEK (DEK Oncogene (DEK))

Reactivité: Humain, Rat, Boeuf (Vache), Lapin, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DEK est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DEK anticorps

Épitope: N-Term

Fonction: DEK Antibody - N-terminal region

Séquence: AAEGEGTPTQ PASEKEPEMP GPREESEEEE DEDDEEEEEE EKEKSLIVEG

Réactivité croisée: Boeuf (Vache), Humain, Rat (Rattus)

Homologie: Cow: 78%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Rabbit: 85%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against DEK. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DEK

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-DEK (ABIN2792543)

Wang, Eckert, Zomorrodi, Xin, Pan, Shearer, Weisz, Maranus, Clawson: "Down-regulation of HtrA1 activates the epithelial-mesenchymal transition and ATM DNA damage response pathways." dans: PLoS ONE, Vol. 7, Issue 6, pp. e39446, (2012) (PubMed).

Détails sur DEK

Antigène: DEK (DEK Oncogene (DEK))

Autre désignation: DEK

Sujet:

Background Information: DEK was first identified in a fusion with the CAN nucleoporin protein in a specific subtype of acute myelogenous leukemia. DEK has also been shown to be an autoantigen in patients with pauciarticular onset juvenile rheumatoid arthritis. Further, the last 65 amino acids of DEK can partially reverse the mutation-prone phenotype of cells from patients with ataxia-telangiectasia

Gene Name: DEK oncogene

Alternative Symbols: D6S231E

Protein Name: Protein DEK

Poids moléculaire: 43kDa

ID gène: 7913

NCBI Accession: NP_003463

UniProt: P35659