ETV6 anticorps (C-Term)

N° du produit ABIN2792592

Cet anticorps Lapin Polyclonal détecte spécifiquement ETV6 dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Chien, Cheval, Lapin et Cobaye.

Aperçu rapide pour ETV6 anticorps (C-Term) (ABIN2792592)

Antigène: ETV6 (Ets Variant 6 (ETV6))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Chien, Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ETV6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-ETV6 anticorps

Épitope: C-Term

Séquence: VSVSPPEEHA MPIGRIADCR LLWDYVYQLL SDSRYENFIR WEDKESKIFR

Réactivité croisée: Boeuf (Vache), Chien, Poulet, Humain, Souris, Rat (Rattus)

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against ETV6. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ETV6

Information d'application

Indications d'application: WB Suggested Anti-ETV6 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: Jurkat cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 452 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ETV6

Antigène: ETV6 (Ets Variant 6 (ETV6))

Autre désignation: ETV6 / TEL1

Sujet: ETV6 (ETS-related protein Tel1, ETS translocation variant 6 , Tel) is an ETS family transcription factor. This protein contains two functional domains: a N-terminal pointed (PNT) domain that is involved in the protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in the protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: TEL, TEL/ABL
Protein Interaction Partner: AP1M1, WDYHV1, UBC, SUMO1, NEDD8, ETV6, SUMO2, PIN1, HDAC6, SOX2, TRAF3, SOCS3, SOCS1, PDGFRB, ELAVL1, UBE2I, NCOR1, SIN3A, HDAC3, L3MBTL1, SMURF1, HDAC9, KAT5, FLI1, IRF8, SKP1, FBXL6, GAB2, GRB2, CRKL, ACTA1,
Protein Size: 452

Poids moléculaire: 53 kDa

ID gène: 2120

NCBI Accession: NM_001987, NP_001978

UniProt: P41212