ETV6 anticorps (C-Term)

N° du produit ABIN2792592

Détail du produit anti-ETV6 anticorps

Antigène: ETV6 (Ets Variant 6 (ETV6))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Lapin, Chien, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ETV6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: VSVSPPEEHA MPIGRIADCR LLWDYVYQLL SDSRYENFIR WEDKESKIFR

Réactivité croisée: Boeuf (Vache), Chien, Poulet, Humain, Souris, Rat (Rattus)

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against ETV6. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ETV6

Information d'application

Indications d'application: WB Suggested Anti-ETV6 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: Jurkat cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 452 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ETV6

Antigène: ETV6 (Ets Variant 6 (ETV6))

Autre désignation: ETV6 / TEL1 (ETV6 Produits)

Synonymes: anticorps etv-6, anticorps tel, anticorps tel/abl, anticorps AW123102, anticorps AW557856, anticorps Tel, anticorps TEL, anticorps id:ibd2308, anticorps TEL/ABL, anticorps cmlc2, anticorps mylc2a, anticorps zgc:92755, anticorps ETS variant 6, anticorps ets variant 6, anticorps myosin, light chain 7, regulatory, anticorps etv6, anticorps Etv6, anticorps ETV6, anticorps myl7

Sujet: ETV6 (ETS-related protein Tel1, ETS translocation variant 6 , Tel) is an ETS family transcription factor. This protein contains two functional domains: a N-terminal pointed (PNT) domain that is involved in the protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in the protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: TEL, TEL/ABL
Protein Interaction Partner: AP1M1, WDYHV1, UBC, SUMO1, NEDD8, ETV6, SUMO2, PIN1, HDAC6, SOX2, TRAF3, SOCS3, SOCS1, PDGFRB, ELAVL1, UBE2I, NCOR1, SIN3A, HDAC3, L3MBTL1, SMURF1, HDAC9, KAT5, FLI1, IRF8, SKP1, FBXL6, GAB2, GRB2, CRKL, ACTA1,
Protein Size: 452

Poids moléculaire: 53 kDa

ID gène: 2120

NCBI Accession: NM_001987, NP_001978

UniProt: P41212