GATA1 anticorps (N-Term)
Aperçu rapide pour GATA1 anticorps (N-Term) (ABIN2792607)
Antigène
Voir toutes GATA1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- SGPEGLDAAA SSTAPSTATA AAAALAYYRD AEAYRHSPVF QVYPLLNCME
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Réactivité croisée
- Boeuf (Vache), Chien, Humain, Souris, Rat (Rattus)
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%, Sheep: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against GATA1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human GATA1
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Indications d'application
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WB Suggested Anti-GATA1 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:312500
Positive Control: MCF7 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. -
Commentaires
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Antigen size: 413 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "GATA-1 binding sites in exon 1 direct erythroid-specific transcription of PPOX." dans: Gene, Vol. 409, Issue 1-2, pp. 83-91, (2008) (PubMed).
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: "GATA-1 binding sites in exon 1 direct erythroid-specific transcription of PPOX." dans: Gene, Vol. 409, Issue 1-2, pp. 83-91, (2008) (PubMed).
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- GATA1 (GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1))
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Autre désignation
- GATA1
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Sujet
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GATA1 is a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ERYF1, GF1, NFE1, GF-1, XLTT, GATA-1
Protein Interaction Partner: KRTAP10-5, CCDC24, HEXIM2, FBF1, KRTAP9-2, RADIL, FRS3, PRKAB2, HSPB1, HOXA1, AKT1, SPIB, SPI1, PRKAA1, HSPA4, FLI1, CASP3, SRA1, SUMO1, CEBPE, MAPK6, UBC, SKI, NME1, RAI1, ZBTB22, TRIM25, TAF7, TAX1BP3, ZZZ3, TRIM29, IKZF1, Rb1, ZFPM1, ZNF521, ZBTB16, HD
Protein Size: 413 -
Poids moléculaire
- 43 kDa
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ID gène
- 2623
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NCBI Accession
- NM_002049, NP_002040
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UniProt
- P15976
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Pathways
- Cellular Response to Molecule of Bacterial Origin
Antigène
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