GATA1 anticorps (N-Term)

N° du produit ABIN2792607

Détail du produit anti-GATA1 anticorps

Antigène: GATA1 (GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Mouton, Boeuf (Vache), Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GATA1 est non-conjugé

Application: Western Blotting (WB)

Séquence: SGPEGLDAAA SSTAPSTATA AAAALAYYRD AEAYRHSPVF QVYPLLNCME

Réactivité croisée: Boeuf (Vache), Chien, Humain, Souris, Rat (Rattus)

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against GATA1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human GATA1

Information d'application

Indications d'application: WB Suggested Anti-GATA1 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:312500
Positive Control: MCF7 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 413 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-GATA1 (ABIN2792607)

de Vooght, van Wijk, van Solinge: "GATA-1 binding sites in exon 1 direct erythroid-specific transcription of PPOX." dans: Gene, Vol. 409, Issue 1-2, pp. 83-91, (2008) (PubMed).

Détails sur GATA1

Antigène: GATA1 (GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1))

Autre désignation: GATA1 (GATA1 Produits)

Synonymes: anticorps ERYF1, anticorps GATA-1, anticorps GF-1, anticorps GF1, anticorps NF-E1, anticorps NFE1, anticorps XLANP, anticorps XLTDA, anticorps XLTT, anticorps Gata-1, anticorps Gf-1, anticorps eryf1, anticorps Eryf1, anticorps GATA1, anticorps gata-1, anticorps Gata1, anticorps si:dkeyp-77f7.5, anticorps gata1, anticorps gata1a-A, anticorps xGATA-1, anticorps xgata1, anticorps XGATA-1B, anticorps gata1b-A, anticorps gta1, anticorps zg1, anticorps NF-E1a, anticorps GATA binding protein 1, anticorps GATA binding protein 1 (globin transcription factor 1), anticorps amidase, anticorps aspartyl/glutamyl-tRNA amidotransferase subunit A, anticorps putative amidase, anticorps GatA1, anticorps glutamyl-tRNA amidotransferase subunit A, anticorps hematopietic transcription factor GATA-1, anticorps GATA binding protein 1b, anticorps GATA binding protein 1 L homeolog, anticorps GATA binding protein 1 S homeolog, anticorps GATA binding protein 1a, anticorps erythroid transcription factor, anticorps GATA1, anticorps Gata1, anticorps gatA1, anticorps gata-1, anticorps gata1b, anticorps gata1.L, anticorps gata1.S, anticorps gata1a, anticorps LOC108348091

Sujet: GATA1 is a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ERYF1, GF1, NFE1, GF-1, XLTT, GATA-1
Protein Interaction Partner: KRTAP10-5, CCDC24, HEXIM2, FBF1, KRTAP9-2, RADIL, FRS3, PRKAB2, HSPB1, HOXA1, AKT1, SPIB, SPI1, PRKAA1, HSPA4, FLI1, CASP3, SRA1, SUMO1, CEBPE, MAPK6, UBC, SKI, NME1, RAI1, ZBTB22, TRIM25, TAF7, TAX1BP3, ZZZ3, TRIM29, IKZF1, Rb1, ZFPM1, ZNF521, ZBTB16, HD
Protein Size: 413

Poids moléculaire: 43 kDa

ID gène: 2623

NCBI Accession: NM_002049, NP_002040

UniProt: P15976

Pathways: Cellular Response to Molecule of Bacterial Origin