CEBPA anticorps (N-Term)

N° du produit ABIN2792649

Cet anticorps Lapin Polyclonal détecte spécifiquement CEBPA dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Cobaye et Porc.

Aperçu rapide pour CEBPA anticorps (N-Term) (ABIN2792649)

Antigène: CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CEBPA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CEBPA anticorps

Épitope: N-Term

Séquence: GGICEHETSI DISAYIDPAA FNDEFLADLF QHSRQQEKAK AAVGPTGGGG

Réactivité croisée: Boeuf (Vache), Humain, Souris, Rat (Rattus)

Homologie: Cow: 100%, Guinea Pig: 90%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CEBPA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CEBPA

Information d'application

Indications d'application: WB Suggested Anti-CEBPA Antibody Titration: 0.2-1 µg/mL
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 358 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CEBPA

Antigène: CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

Autre désignation: CEBPA

Sujet: CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. It has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, CEBPA can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.
Alias Symbols: CEBP, C/EBP-alpha
Protein Interaction Partner: CEBPB, ZBTB16, RARA, HDAC1, BHLHE41, UBC, CEBPE, BATF2, BATF3, YY1AP1, ATF5, BATF, FOSL1, FOS, DBP, CEBPG, CEBPA, ATF4, ATF3, UBE3A, SKP2, RASGRF1, C1QBP, CDKN1A, SRA1, CDK4, PIAS1, Fbxw7, GRIN3A, RAB34, NAA16, POLR1E, MRTO4, AK5, MACF1, KAT5, AKAP9, SMC1
Protein Size: 358

Poids moléculaire: 38 kDa

ID gène: 1050

NCBI Accession: NM_004364, NP_004355

UniProt: P49715

Pathways: Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation