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SUB1 anticorps (Middle Region)

SUB1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Saccharomyces cerevisiae WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2792675
  • Antigène Voir toutes SUB1 Anticorps
    SUB1 (Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1))
    Épitope
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 34
    • 12
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Saccharomyces cerevisiae
    Hôte
    • 32
    • 2
    Lapin
    Clonalité
    • 33
    • 1
    Polyclonal
    Conjugué
    • 23
    • 3
    • 3
    • 3
    • 1
    • 1
    Cet anticorp SUB1 est non-conjugé
    Application
    • 28
    • 18
    • 14
    • 8
    • 6
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    NMFQIGKMRY VSVRDFKGKV LIDIREYWMD PEGEMKPGRK GISLNPEQWS
     Réactivité croisée
    Boeuf (Vache), Chien, Poulet, Humain, Souris, Rat (Rattus)
    Homologie
    Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against PC4. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human PC4
    Top Product
    Discover our top product SUB1 Anticorps primaire
  • Indications d'application
    WB Suggested Anti-PC4 Antibody Titration: 0.5-1.0 µg/mL
    Positive Control: HepG2 cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 127 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    SUB1 (Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1))
    Autre désignation
    SUB1 / PC4 (SUB1 Produits)
    Synonymes
    anticorps P15, anticorps PC4, anticorps p14, anticorps AI842364, anticorps P9, anticorps Pc4, anticorps Rpo2tc1, anticorps SUB1 homolog, transcriptional regulator, anticorps SUB1 homolog (S. cerevisiae), anticorps SUB1, anticorps Sub1
    Sujet
    PC4 (activated RNA polymerase II transcription cofactor 4) is a transcriptional coactivator, possessing the ability to suppress promoter-driven as well as nonspecific transcription via its DNA binding activity. The repressive activity of PC4 on promoter-driven transcription is alleviated by transcription factor TFIIH. TFIIH protects promoters from PC4-mediated repression by relieving the topological constraint imposed by PC4 through the ERCC3 helicase activity.
    Alias Symbols: P15, PC4, p14
    Protein Interaction Partner: HUWE1, SUB1, UBC, rev, CLK4, CDK2, HNF4A, FN1, CSNK2A1, SMURF1, RPL18A, LAMP2, CDC5L, APP, YWHAZ, GTF3C1, ELAVL1, SUMO2, HDGF, Shoc2, Kif1c, POLR2B, POLR2A, CBX5, RCOR1, REST, BANF1, ADAP1, GTF2A1L, EP300, POU2AF1, CSTF2, TBP, TAF1, PCNA, HSF1, PSIP1, SP1
    Protein Size: 127
    Poids moléculaire
    14 kDa
    ID gène
    10923
    NCBI Accession
    NM_006713, NP_006704
    UniProt
    P53999
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