GTF2B anticorps (N-Term)

N° du produit ABIN2792692

L’anticorps Lapin Polyclonal anti-GTF2B a été validé pour WB et IHC. Il convient pour détecter GTF2B dans des échantillons de Humain, Souris, Chien, Poisson zèbre (Danio rerio), Cheval, Cobaye et Lapin. Il y a 1 publication disponible.

Aperçu rapide pour GTF2B anticorps (N-Term) (ABIN2792692)

Antigène: GTF2B (General Transcription Factor IIB (GTF2B))

Reactivité: Humain, Souris, Chien, Poisson zèbre (Danio rerio), Cheval, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GTF2B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-GTF2B anticorps

Épitope: N-Term

Séquence: NLPRNIVDRT NNLFKQVYEQ KSLKGRANDA IASACLYIAC RQEGVPRTFK

Réactivité croisée: Boeuf (Vache), Chien, Humain, Souris, Rat (Rattus)

Homologie: Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against GTF2B. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human GTF2B

Information d'application

Indications d'application: WB Suggested Anti-GTF2B Antibody Titration: 4.0 µg/mL
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 316 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-GTF2B (ABIN2792692)

Tubon, Tansey, Herr: "A nonconserved surface of the TFIIB zinc ribbon domain plays a direct role in RNA polymerase II recruitment." dans: Molecular and cellular biology, Vol. 24, Issue 7, pp. 2863-74, (2004) (PubMed).

Détails sur GTF2B

Antigène: GTF2B (General Transcription Factor IIB (GTF2B))

Autre désignation: GTF2B

Sujet: GTF2B is the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.
Alias Symbols: TF2B, TFIIB
Protein Interaction Partner: DRAP1, TNIP1, UBC, FBXO25, HNF4A, TCEA1, GTF2F2, GTF2F1, DEPDC7, SLC22A2, RELA, POLR2C, JAK3, HMGCL, SMURF1, THRA, TBP, POLR2E, SRA1, LSM4, LSM5, CIITA, NXF1, POU3F2, EP300, PSMA3, POLR2J, ESR1, UL48, NR1D2, NCOR1, TAF9, REST, tat, SAP25, MKX, CTDP1, POLR
Protein Size: 316

Poids moléculaire: 35 kDa

ID gène: 2959

NCBI Accession: NM_001514, NP_001505

UniProt: Q00403