GTF2B anticorps (N-Term)
Aperçu rapide pour GTF2B anticorps (N-Term) (ABIN2792692)
Antigène
Voir toutes GTF2B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- GTF2B Antibody - N-terminal region
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Séquence
- NLPRNIVDRT NNLFKQVYEQ KSLKGRANDA IASACLYIAC RQEGVPRTFK
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Réactivité croisée
- Boeuf (Vache), Chien, Humain, Souris, Rat (Rattus)
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Homologie
- Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Zebrafish: 92%
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Attributs du produit
- This is a rabbit polyclonal antibody against GTF2B. It was validated on Western Blot and immunohistochemistry.
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Purification
- Protein A purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human GTF2B
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "A nonconserved surface of the TFIIB zinc ribbon domain plays a direct role in RNA polymerase II recruitment." dans: Molecular and cellular biology, Vol. 24, Issue 7, pp. 2863-74, (2004) (PubMed).
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- GTF2B (General Transcription Factor IIB (GTF2B))
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Autre désignation
- GTF2B
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Sujet
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Background Information: GTF2B is the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.
Gene Name: General transcription factor IIB
Alternative Symbols: TF2B, TFIIB
Protein Name: Transcription initiation factor IIB
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Poids moléculaire
- 35kDa
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ID gène
- 2959
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NCBI Accession
- NP_001505
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UniProt
- Q00403
Antigène
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