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Nucleobindin 1 anticorps (C-Term)

NUCB1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2792698
  • Antigène Voir toutes Nucleobindin 1 (NUCB1) Anticorps
    Nucleobindin 1 (NUCB1)
    Épitope
    • 15
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 33
    • 20
    • 19
    • 2
    Humain
    Hôte
    • 32
    • 4
    Lapin
    Clonalité
    • 34
    • 2
    Polyclonal
    Conjugué
    • 22
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Nucleobindin 1 est non-conjugé
    Application
    • 34
    • 13
    • 13
    • 10
    • 9
    • 7
    • 6
    • 5
    • 5
    • 3
    • 1
    Western Blotting (WB)
    Séquence
    PAAHPEGQLK FHPDTDDVPV PAPAGDQKEV DTSEKKLLER LPEVEVPQHL
     Réactivité croisée
    Humain
    Homologie
    Human: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against NUCB1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C terminal region of human NUCB1
    Top Product
    Discover our top product NUCB1 Anticorps primaire
  • Indications d'application
    WB Suggested Anti-NUCB1 Antibody Titration: 0.2-1 µg/mL
    ELISA Titer: 1:1562500
    Positive Control: HepG2 cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 461 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Bonito-Oliva, Barbash, Sakmar, Graham: "Nucleobindin 1 binds to multiple types of pre-fibrillar amyloid and inhibits fibrillization." dans: Scientific reports, Vol. 7, pp. 42880, (2017) (PubMed).

    Larkin, Ribeiro, Lavoie: "Topology and membrane anchoring of the lysosomal storage disease-related protein CLN5." dans: Human mutation, Vol. 34, Issue 12, pp. 1688-97, (2013) (PubMed).

    Lin, Fischer, Lavoie, Huang, Farquhar: "Calnuc plays a role in dynamic distribution of Galphai but not Gbeta subunits and modulates ACTH secretion in AtT-20 neuroendocrine secretory cells." dans: Molecular neurodegeneration, Vol. 4, pp. 15, (2009) (PubMed).

    Valencia, Cotten, Duan, Liu: "Modulation of nucleobindin-1 and nucleobindin-2 by caspases." dans: FEBS letters, Vol. 582, Issue 2, pp. 286-90, (2008) (PubMed).

    Sugeno, Takeda, Hasegawa, Kobayashi, Kikuchi, Mori, Wakabayashi, Itoyama: "Serine 129 phosphorylation of alpha-synuclein induces unfolded protein response-mediated cell death." dans: The Journal of biological chemistry, Vol. 283, Issue 34, pp. 23179-88, (2008) (PubMed).

    Lin, Li, Zhang, Huang, Tong, Farquhar, Xu: "Calnuc binds to Alzheimer's beta-amyloid precursor protein and affects its biogenesis." dans: Journal of neurochemistry, Vol. 100, Issue 6, pp. 1505-14, (2007) (PubMed).

  • Antigène
    Nucleobindin 1 (NUCB1)
    Autre désignation
    Nucleobindin-1 (NUCB1 Produits)
    Synonymes
    anticorps nuc, anticorps MGC69294, anticorps MGC81496, anticorps NUCB1, anticorps zgc:153192, anticorps DKFZp459O1814, anticorps B230337F23Rik, anticorps C77483, anticorps Calnuc, anticorps MTEST82, anticorps Nucb, anticorps CALNUC, anticorps NUC, anticorps nucleobindin 1, anticorps nucleobindin 1 S homeolog, anticorps nucb1, anticorps nucb1.S, anticorps NUCB1, anticorps Nucb1
    Sujet
    Nucleobindin, also known as calnuc, participates in Ca2+ storage in the Golgi, as well as in other biological processes that involve DNA-binding and protein-protein interactions.
    Alias Symbols: NUC, CALNUC
    Protein Interaction Partner: REL, UBC, MDM2, CTPS2, RAD23B, PRKDC, METTL1, GTF2I, CBS, XPNPEP1, WARS, PTGS2, XPO1, SET, RBL1, MYC, HIVEP1, GNAS, GNAI3, GNAI1, KLC4, PTGS1, NDN, GNAI2, GNAO1, GNAZ,
    Protein Size: 461
    Poids moléculaire
    54 kDa
    ID gène
    4924
    NCBI Accession
    NM_006184, NP_006175
    UniProt
    Q02818
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