PDX1 anticorps (C-Term)

N° du produit ABIN2793201

Détail du produit anti-PDX1 anticorps

Antigène: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Épitope: AA 186-215, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDX1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Fonction: Rabbit Anti-Human IPF (C-term) Antibody

Immunogène: This IPF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-215 amino acids from the C-terminal region of human IPF.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot, Immunofluorescence
Recommended Dilutions
WB: 1:1000, IF: 1:10-50Ipf Antibody (C-term) . IPF immunoreactivity is localized to Cytoplasm and Nucleus significantly.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2.0 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur PDX1

Antigène: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Autre désignation: IPF (PDX1 Produits)

Synonymes: anticorps GSF, anticorps IDX-1, anticorps IPF1, anticorps IUF1, anticorps MODY4, anticorps PDX-1, anticorps STF-1, anticorps ipf1, anticorps PDX1, anticorps IPF-1, anticorps Ipf1, anticorps Mody4, anticorps pdx-1, anticorps Idx1, anticorps Stf1, anticorps zgc:100874, anticorps XlHbox-8, anticorps xlhbox8, anticorps pancreatic and duodenal homeobox 1, anticorps pancreatic and duodenal homeobox 1 S homeolog, anticorps PDX1, anticorps pdx1, anticorps Pdx1, anticorps pdx1.S

Sujet:

Target Description: IPF is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. This nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

Gene Symbol: PDX1

Poids moléculaire: 30771 Da

ID gène: 3651

UniProt: P52945

Pathways: Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location