PDX1 anticorps (C-Term)

N° du produit ABIN2793201

Cet anticorps anti-PDX1 Polyclonal Lapin (ABIN2793201) détecte spécifiquement PDX1 dans WB, IF et IP. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PDX1 anticorps (C-Term) (ABIN2793201)

Antigène: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDX1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Détail du produit anti-PDX1 anticorps

Épitope: AA 186-215, C-Term

Fonction: Rabbit Anti-Human IPF (C-term) Antibody

Immunogène: This IPF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-215 amino acids from the C-terminal region of human IPF.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot, Immunofluorescence
Recommended Dilutions
WB: 1:1000, IF: 1:10-50Ipf Antibody (C-term) . IPF immunoreactivity is localized to Cytoplasm and Nucleus significantly.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2.0 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur PDX1

Antigène: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Autre désignation: IPF

Sujet:

Target Description: IPF is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. This nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).

Gene Symbol: PDX1

Poids moléculaire: 30771 Da

ID gène: 3651

UniProt: P52945

Pathways: Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location