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CFLA anticorps (Center)

VVL Reactivité: Humain FACS, IHC, WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2793618
  • Antigène
    CFLA (VVL) (POU Domain Protein CF1A (VVL))
    Épitope
    AA 145-174, Center
    Reactivité
    Humain
    Hôte
    Lapin
    Clonalité
    Polyclonal
    Application
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB)
    Fonction
    Rabbit Anti-Human CFLAR (Center) Antibody
    Immunogène
    This CFLAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-174 amino acids from the Central region of human CFLAR.
    Isotype
    Ig Fraction
  • Indications d'application
    Western Blot, Immunohistochemistry, Flow Cytometry
    Recommended Dilutions
    WB: 1:1000, IHC: 1:50-100, FC: 1:10-50Western blot analysis of CFLAR Antibody (Center) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    2.000 mg/mL
    Stock
    4 °C,-20 °C
    Stockage commentaire
    2-8°C (short-term), -20°C (long-term)
  • Antigène
    CFLA (VVL) (POU Domain Protein CF1A (VVL))
    Autre désignation
    CFLA
    Sujet

    Target Description: Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. It acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. It lacks enzymatic (caspase) activity.

    Gene Symbol: CFLAR

    Poids moléculaire
    55344 Da
    ID gène
    8837
    UniProt
    O15519
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