RSPH1 anticorps (C-Term)
Aperçu rapide pour RSPH1 anticorps (C-Term) (ABIN2796441)
Antigène
Voir toutes RSPH1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 532-558, C-Term
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Fonction
- Rabbit Anti-Human MCAM (C-term) Antibody
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Immunogène
- This MCAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 532-558 amino acids from the C-terminal region of human MCAM.
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Isotype
- Ig Fraction
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Indications d'application
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50Western blot analysis of MCAM Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.300 mg/mL
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C (short-term), -20°C (long-term)
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- RSPH1 (Radial Spoke Head 1 Homolog (RSPH1))
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Autre désignation
- MCA
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Sujet
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Target Description: MCAM plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. It could be an adhesion molecule active in neural crest cells during embryonic development. It acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.
Gene Symbol: MCAM
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Poids moléculaire
- 71607 Da
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ID gène
- 4162
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UniProt
- P43121
Antigène
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