WT1 anticorps (AA 346-375)

N° du produit ABIN2797552

Cet anticorps Lapin Polyclonal détecte spécifiquement WT1 dans IHC, IF, FACS et WB. Il présente une réactivité envers Humain.

Aperçu rapide pour WT1 anticorps (AA 346-375) (ABIN2797552)

Antigène: WT1 (Wilms Tumor 1 (WT1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WT1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Western Blotting (WB)

Détail du produit anti-WT1 anticorps

Épitope: AA 346-375

Fonction: Rabbit Anti-Human WT1 (Center E361) Antibody

Immunogène: This WT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-375 amino acids from the Central region of human WT1.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100, IF: 1:10-50, FC: 1:10-50WT1 Antibody (Center E361) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.300 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur WT1

Antigène: WT1 (Wilms Tumor 1 (WT1))

Autre désignation: WT1

Sujet:

Target Description: This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq].

Gene Symbol: WT1

Poids moléculaire: 49188 Da

ID gène: 7490

UniProt: P19544

Pathways: Tube Formation