MID1 anticorps (C-Term)
Aperçu rapide pour MID1 anticorps (C-Term) (ABIN2798159)
Antigène
Voir toutes MID1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 575-603, C-Term
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Fonction
- Rabbit Anti-Human MID1 (C-term) Antibody
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Immunogène
- This MID1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 575-603 amino acids from the C-terminal region of human MID1.
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Isotype
- Ig Fraction
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Indications d'application
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Western Blot
Recommended Dilutions
WB: 1:1000MID1 Antibody (C-term) . -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C (short-term), -20°C (long-term)
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- MID1 (Midline 1 (MID1))
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Autre désignation
- MID1
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Sujet
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Target Description: The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Multiple different transcript variants are generated by alternate splicing, however, the full-length nature of some of the variants has not been determined.
Gene Symbol: MID1
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Poids moléculaire
- 75251 Da
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ID gène
- 4281
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UniProt
- O15344
Antigène
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