CDH6 anticorps (C-Term)
Aperçu rapide pour CDH6 anticorps (C-Term) (ABIN2798460)
Antigène
Voir toutes CDH6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 665-695, C-Term
-
Fonction
- Rabbit Anti-Human K Cadherin (CDH6) (C-term) Antibody
-
Immunogène
- This K Cadherin (CDH6) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 665-695 amino acids from the C-terminal region of human K Cadherin (CDH6).
-
Isotype
- Ig Fraction
-
-
-
-
Indications d'application
-
Western Blot, Immunohistochemistry, Flow Cytometry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50, FC: 1:10-50Western blot analysis of anti-DH6 Antibody (C-term) (RB14082) in 293 cell line lysates (35 μg/lane). DH6(arrow) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with CDH6 antibody (C-term) . FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. -
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.5 mg/mL
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- 2-8°C (short-term), -20°C (long-term)
-
-
- CDH6 (K-Cadherin (CDH6))
-
Autre désignation
- K Cadherin
-
Sujet
-
Target Description: CDH6 is a type II classical cadherin from the cadherin superfamily. It is a calcium dependent cell-cell adhesion membrane glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of the CDH6 gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion.
Gene Symbol: CDH6
-
Poids moléculaire
- 88309 Da
-
ID gène
- 1004
-
UniProt
- P55285
-
Pathways
- Cell-Cell Junction Organization
Antigène
-