RNF19A anticorps (Center)

N° du produit ABIN2798497

Cet anticorps Lapin Polyclonal détecte spécifiquement RNF19A dans WB et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour RNF19A anticorps (Center) (ABIN2798497)

Antigène: RNF19A (Ring Finger Protein 19A (RNF19A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF19A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-RNF19A anticorps

Épitope: AA 384-413, Center

Fonction: Rabbit Anti-Human RNF19A (Center) Antibody

Immunogène: This RNF19A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 384-413 amino acids from the Central region of human RNF19A.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50RNF19A Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur RNF19A

Antigène: RNF19A (Ring Finger Protein 19A (RNF19A))

Autre désignation: RNF19A

Sujet:

Target Description: The protein encoded this gene contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB. Alternatively spliced transcript variants encoding the same protein have been reported.

Gene Symbol: RNF19A

Poids moléculaire: 90696 Da

ID gène: 25897

UniProt: Q9NV58