Desmoglein 1 anticorps (Center)
Aperçu rapide pour Desmoglein 1 anticorps (Center) (ABIN2798593)
Antigène
Voir toutes Desmoglein 1 (DSG1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 471-499, Center
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Fonction
- Rabbit Anti-Human DSG1 (Center) Antibody
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Immunogène
- This DSG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 471-499 amino acids from the Central region of human DSG1.
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Isotype
- Ig Fraction
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Indications d'application
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50DSG1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 2-8°C (short-term), -20°C (long-term)
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- Desmoglein 1 (DSG1)
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Autre désignation
- DSG1
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Sujet
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Target Description: Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus.
Gene Symbol: DSG1
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Poids moléculaire
- 113748 Da
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ID gène
- 1828
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UniProt
- Q02413
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Pathways
- Cell-Cell Junction Organization
Antigène
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