SNX6 anticorps (N-Term)

N° du produit ABIN2798685

Cet anticorps anti-SNX6 est un anticorps Lapin Polyclonal détectant SNX6 dans WB. Adapté pour Humain.

Aperçu rapide pour SNX6 anticorps (N-Term) (ABIN2798685)

Antigène: SNX6 (Sorting Nexin 6 (SNX6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNX6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SNX6 anticorps

Épitope: AA 81-110, N-Term

Fonction: Rabbit Anti-Human SNX6 (N-term) Antibody

Immunogène: This SNX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-110 amino acids from the N-terminal region of human SNX6.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of SNX6 Antibody (N-term) was detected using the purified Pab.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2.0 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur SNX6

Antigène: SNX6 (Sorting Nexin 6 (SNX6))

Autre désignation: SNX6

Sujet:

Target Description: SNX6 interacts with members of the transforming growth factor-beta family of receptor serine-threonine kinases. These receptors belong to two classes: type II receptors that bind ligand, and type I receptors that are subsequently recruited to transduce the signal. Of the type II receptors, SNX6 was found to interact strongly with ActRIIB and more moderately with wild type and kinase-defective mutants of TbetaRII. Of the type I receptors, SNX6 was found to interact only with inactivated TbetaRI. SNXs 1-4 also interacted with the transforming growth factor-beta receptor family, showing different receptor preferences. Conversely, SNX6 behaved similarly to the other SNX proteins in its interactions with receptor tyrosine kinases. Strong heteromeric interactions were also seen among SNX1, -2, -4, and -6, suggesting the formation in vivo of oligomeric complexes. These findings are the first evidence for the association of the SNX family of molecules with receptor serine-threonine kinases.

Gene Symbol: SNX6

Poids moléculaire: 46649 Da

ID gène: 58533

UniProt: Q9UNH7

Pathways: EGFR Signaling Pathway