PDZK1 anticorps (Center)

N° du produit ABIN2798783

L’anticorps Lapin Polyclonal anti-PDZK1 a été validé pour WB et IHC. Il convient pour détecter PDZK1 dans des échantillons de Humain.

Aperçu rapide pour PDZK1 anticorps (Center) (ABIN2798783)

Antigène: PDZK1 (PDZ Domain Containing 1 (PDZK1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDZK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-PDZK1 anticorps

Épitope: AA 196-224, Center

Fonction: Rabbit Anti-Human PDZK1 (Center) Antibody

Immunogène: This PDZK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-224 amino acids from the Central region of human PDZK1.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50PDZK1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.350 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur PDZK1

Antigène: PDZK1 (PDZ Domain Containing 1 (PDZK1))

Autre désignation: PDZK1

Sujet:

Target Description: A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. May function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism. May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function (By similarity).

Gene Symbol: PDZK1

Poids moléculaire: 57129 Da

ID gène: 5174

UniProt: Q5T2W1