SMYD2A anticorps (AA 351-433)

N° du produit ABIN2803151

Cet anticorps Lapin Polyclonal détecte spécifiquement SMYD2A dans WB, IHC (p), IHC (fro), IF (cc) et IF (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour SMYD2A anticorps (AA 351-433) (ABIN2803151)

Antigène: SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMYD2A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-SMYD2A anticorps

Épitope: AA 351-433

Fonction: KMT3C Polyclonal Antibody

Réactivité croisée: Humain, Souris, Rat

Homologie: Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SMYD2

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000),

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur SMYD2A

Antigène: SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))

Autre désignation: SMYD2

Sujet:

Synonyms: KMT3C, HSKM-B, ZMYND14, N-lysine methyltransferase SMYD2, Histone methyltransferase SMYD2, Lysine N-methyltransferase 3C, SET and MYND domain-containing protein 2, SMYD2

Background: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'.

ID gène: 56950

UniProt: Q9NRG4