SMYD2A anticorps (AA 351-433)

N° du produit ABIN2803151

Détail du produit anti-SMYD2A anticorps

Antigène: SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))

Épitope: AA 351-433

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMYD2A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris

Homologie: Rat,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SMYD2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur SMYD2A

Antigène: SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))

Autre désignation: SMYD2 (SMYD2A Produits)

Synonymes: anticorps HSKM-B, anticorps KMT3C, anticorps ZMYND14, anticorps 1110020E07Rik, anticorps 4930402C15, anticorps Zmynd14, anticorps smyd2-a, anticorps im:7146196, anticorps smyd2, anticorps wu:fc02f02, anticorps zgc:110553, anticorps si:dkey-121j17.3, anticorps zgc:136609, anticorps SET and MYND domain containing 2, anticorps SET and MYND domain containing 2 S homeolog, anticorps SET and MYND domain containing 2a, anticorps SET and MYND domain containing 2b, anticorps SMYD2, anticorps Smyd2, anticorps smyd2.S, anticorps smyd2a, anticorps smyd2b

Sujet:

Synonyms: KMT3C, HSKM-B, ZMYND14, N-lysine methyltransferase SMYD2, Histone methyltransferase SMYD2, Lysine N-methyltransferase 3C, SET and MYND domain-containing protein 2, SMYD2

Background: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'.

ID gène: 56950

UniProt: Q9NRG4