MORG1 anticorps (AA 201-315) (AbBy Fluor® 594)
Aperçu rapide pour MORG1 anticorps (AA 201-315) (AbBy Fluor® 594) (ABIN2803990)
Antigène
Voir toutes MORG1 (wdr83) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 201-315
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Réactivité croisée
- Souris, Rat
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Homologie
- Human,Dog,Cow,Pig,Horse,Rabbit
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human MAPK organizer 1
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Isotype
- IgG
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Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))
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Autre désignation
- MAPK organizer 1
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Sujet
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Synonyms: MORG1, WD repeat domain-containing protein 83, Mitogen-activated protein kinase organizer 1, MAPK organizer 1, WDR83
Background: Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream activator (By similarity). May also be involved in pre-mRNA splicing.
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ID gène
- 84292
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UniProt
- Q9BRX9
Antigène
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