T-Bet anticorps (AbBy Fluor® 594)

N° du produit ABIN2806926

Cet anticorps Lapin Polyclonal détecte spécifiquement T-Bet dans WB et IF (p). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour T-Bet anticorps (AbBy Fluor® 594) (ABIN2806926)

Antigène: T-Bet

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp T-Bet est conjugé à/à la AbBy Fluor® 594

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-T-Bet anticorps (AbBy Fluor® 594)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Tbx21

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur T-Bet

Antigène: T-Bet

Autre désignation: Tbx21/ T-Bet

Sujet:

Synonyms: T bet, T box 21, T box expressed in T cells, T box protein 21, T box transcription factor TBX21, T cell specic T box transcription factor, T cell specic T box transcription factor T bet, T PET, TBET, TBLYM, TBX 21, TBX21, TPET, Transcription factor TBLYM, TBX21_HUMAN, T-box transcription factor TBX21, T-box protein 21, T-cell-specic T-box transcription factor T-bet, Transcription factor TBLYM.

Background: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. [provided by RefSeq, Jul 2008].

ID gène: 30009