TRIM32 anticorps (AA 301-400) (AbBy Fluor® 594)

N° du produit ABIN2807199

Cet anticorps Lapin Polyclonal détecte spécifiquement TRIM32 dans WB, FACS, IF (cc) et IF (p). Il présente une réactivité envers Souris.

Aperçu rapide pour TRIM32 anticorps (AA 301-400) (AbBy Fluor® 594) (ABIN2807199)

Antigène: TRIM32 (Tripartite Motif Containing 32 (TRIM32))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIM32 est conjugé à/à la AbBy Fluor® 594

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-TRIM32 anticorps (AbBy Fluor® 594)

Épitope: AA 301-400

Réactivité croisée: Souris

Homologie: Human,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from mouse TRIM32

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur TRIM32

Antigène: TRIM32 (Tripartite Motif Containing 32 (TRIM32))

Autre désignation: TRIM32/BBS11

Sujet:

Synonyms: 72 kda Tat interacting Protein, BBS11, HT2A, LGMD2H, Limb girdle muscular dystrophy 2H autosomal recessive, Limb girdle muscular dystrophy 2H, Muscular dystrophy Hutterite type, TAT interactive protein 72KD, TATIP, Tripartite Mot Containing Protein 32, Zinc Finger Protein HT2A, TRI32_MOUSE.

Background: Tripartite motif-containing protein 32 (TRIM32) belongs to the tripartite motif (TRIM) protein family. TRIM32, like all TRIM proteins, contains a domain structure composed of a B-box, a RING-finger and a coiled-coil motif. Additionally, TRIM32 has six C-terminal NHL domains, it is expressed mainly in the skeletal muscle. The TRIM32 gene encodes an E3 ubiquitin ligase, a protein that attaches ubiquitin to a lysine residue on a target protein and acts in conjunction with ubiquitin-conjugating enzymes UbcH5a, UbcH5c and UbcH6. Mutations in the TRIM32 gene cause two forms of autosomal recessive muscular dystrophy designated limb girdle muscular dystrophy type 2H (LGMD2H) and sarcotubular myopathy (STM). TRIM32 mutations can also result in Bardet-Biedl syndrome (BBS), an autosomal recessive disorder characterized by pigmentary retinopathy, polydactyly, hypogenitalism, renal abnormalities, learning disabilities and obesity.

ID gène: 22954

Pathways: Negative Regulation of intrinsic apoptotic Signaling