BPGM anticorps (AbBy Fluor® 594)

N° du produit ABIN2810396

Cet anticorps anti-BPGM est un anticorps Lapin Polyclonal détectant BPGM dans WB, FACS et IF (p). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour BPGM anticorps (AbBy Fluor® 594) (ABIN2810396)

Antigène: BPGM (2,3-bisphosphoglycerate Mutase (BPGM))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BPGM est conjugé à/à la AbBy Fluor® 594

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-BPGM anticorps (AbBy Fluor® 594)

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human BPGM

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur BPGM

Antigène: BPGM (2,3-bisphosphoglycerate Mutase (BPGM))

Autre désignation: BPGM

Sujet:

Synonyms: 2,3-bisphosphoglycerate mutase, 2,3-bisphosphoglycerate synthase, 3-bisphosphoglycerate mutase, 3-bisphosphoglycerate synthase, 3-diphosphoglycerate mutase, Ab2 098, AI323730, AL022789, Bisphosphoglycerate mutase, BPG dependent PGAM, BPG-dependent PGAM , Bpgm, BPGM, C86192, DPGM, Erythrocyte 2,3 bisphosphoglycerate mutase, PMGE_HUMAN, 2,3-bisphosphoglycerate mutase, erythrocyte, erythrocyte, 2 antibody.

Background: BPGM (2,3-bisphosphoglycerate mutase) is a 259 amino acid protein that belongs to the phosphoglycerate mutase family and exists as a homodimer that plays a crucial role in the regulation of hemoglobin oxygen. Specifically, BPGM catalyzes the conversion of 3-D-glyceroyl phosphate to 2,3-bisD-glycerate (2,3-BPG), a reaction that is essential for controlling the concentration of 2,3-BPG within the cell. The gene encoding BPGM maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5 % of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. Involvement in disease:Defects in BPGM are the cause of bisphosphoglycerate mutase deficiency (BPGMD) . A disease characterized by hemolytic anemia, splenomegaly, cholelithiasis and cholecystitis.

ID gène: 669