FOXH1 anticorps (AA 41-140) (AbBy Fluor® 594)

N° du produit ABIN2813349

Cet anticorps Lapin Polyclonal détecte spécifiquement FOXH1 dans WB, IF (cc) et IF (p). Il présente une réactivité envers Souris.

Aperçu rapide pour FOXH1 anticorps (AA 41-140) (AbBy Fluor® 594) (ABIN2813349)

Antigène: FOXH1 (Forkhead Box H1 (FOXH1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXH1 est conjugé à/à la AbBy Fluor® 594

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-FOXH1 anticorps (AbBy Fluor® 594)

Épitope: AA 41-140

Réactivité croisée: Souris

Homologie: Human,Rat,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FOXH1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur FOXH1

Antigène: FOXH1 (Forkhead Box H1 (FOXH1))

Autre désignation: FOXH1

Sujet:

Synonyms: FAST 1, Fast 2, Fast-1, Fast-2, FAST1, Fast2, Forkhead activin signal transducer 1, Forkhead activin signal transducer 2, Forkhead box H1, Forkhead box protein H1, FOX H1, FOXH 1, FOXH1, FOXH1_HUMAN, hFAST 1, hFAST-1, hFAST1, Human homolog of Xenopus forkhead activin signal transducer 1, TGF beta/Activin signal transducer FAST1.

Background: Xenopus winged-helix factor, xFAST-1 (forkhead activin signal transducer-1) is a transcription factor that forms a complex with the receptor-regulated Smad protein, Smad2, and directly binds to activin response elements on DNA (1,2). The human homolog FAST-1 and the corresponding mouse homolog, designated FAST-2, share significant sequence homology with xFAST-1, including a conserved N-terminal forkhead domain that consists of 110 amino acid residues and is essential for binding DNA and regulating transcription in embryogenesis, in tumorigenesis and in the maintenance of differentiated cell states (3,4). FAST-1 and FAST-2 also contain a distinct C-terminal Smad interaction domain that is required for the association with various Smad proteins, including Smad2, Smad3 and Smad4 (3,5). Expression of FAST-1 and FAST-2 is predominantly observed during early development, with lower levels detected in adult tissues (6,7). FAST-1 and FAST-2 mediated DNA binding is attenuated by both TFGß, and activin, indicating that these FAST proteins mediate TFGß, induced signal transduction (3).

ID gène: 8928

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling