EPRS anticorps (AA 651-750) (AbBy Fluor® 594)

N° du produit ABIN2813834

Cet anticorps anti-EPRS est un anticorps Lapin Polyclonal détectant EPRS dans WB, IF (cc) et IF (p). Adapté pour Humain, Souris et Rat.

Aperçu rapide pour EPRS anticorps (AA 651-750) (AbBy Fluor® 594) (ABIN2813834)

Antigène: EPRS (Glutamyl-Prolyl-tRNA Synthetase (EPRS))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPRS est conjugé à/à la AbBy Fluor® 594

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-EPRS anticorps (AbBy Fluor® 594)

Épitope: AA 651-750

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Glutamyl Prolyl tRNA syntase/ProRS

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur EPRS

Antigène: EPRS (Glutamyl-Prolyl-tRNA Synthetase (EPRS))

Autre désignation: Glutamyl Prolyl tRNA synthetase/ProRS

Sujet:

Synonyms: EARS, PARS, QARS, QPRS, PIG32, GLUPRORS, Bifunctional glutamate/proline--tRNA ligase, Bifunctional aminoacyl-tRNA synthetase, Cell proliferation-inducing gene 32 protein, Glutamatyl-prolyl-tRNA synthetase, EPRS, GLNS

Background: Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the multisynthetase complex and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.

ID gène: 2058

UniProt: P07814