CBX5 anticorps (pTyr43) (AbBy Fluor® 594)

N° du produit ABIN2814480

Cet anticorps Lapin Polyclonal détecte spécifiquement CBX5 dans WB, IF (p) et IF (cc). Il présente une réactivité envers Others.

Aperçu rapide pour CBX5 anticorps (pTyr43) (AbBy Fluor® 594) (ABIN2814480)

Antigène: CBX5 (Chromobox Homolog 5 (CBX5))

Reactivité: Others

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CBX5 est conjugé à/à la AbBy Fluor® 594

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Détail du produit anti-CBX5 anticorps (AbBy Fluor® 594)

Épitope: pTyr43

Réactivité croisée (Details): Fruit Fly

Homologie: Drosophila

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from Drosophila Melanogaster HP1 around the phosphorylation site of Tyr43

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur CBX5

Antigène: CBX5 (Chromobox Homolog 5 (CBX5))

Autre désignation: HP1

Sujet:

Synonyms: Heterochromatin protein 1, HP1, Non-histone chromosomal protein C1A9 antigen, CG8409

Background: HP1 alpha is a component of heterochromatin. It recognizes and binds histone H3 tails methylated at Lys-9, leading to epigenetic repression. HP1 alpha may interact with lamin B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. HP1 proteins are relatively small proteins (~25 kDa) with a conserved amino-terminal chromo domain and a structurally related carboxy-terminal motif, the chromo shadow domain. Both domains of HP1 are required for binding to native chromatin in vivo, but they contribute differentially to binding in euchromatin and heterochromatin.

ID gène: 34119