RUNX2 anticorps (pSer465)

N° du produit ABIN389942

Détail du produit anti-RUNX2 anticorps

Antigène: RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

Épitope: pSer465

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RUNX2 est non-conjugé

Application: Dot Blot (DB)

Specificité: This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S533 of human RUNX2.

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RUNX2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S465 of human RUNX2.

Clone: RB15321

Isotype: Ig Fraction

Information d'application

Indications d'application: DB = 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-RUNX2 (ABIN389942)

Fu, Wang, Lu, Ma, Ke, Liu, Luo: "In vitro inhibitory effects of terpenoids from Chloranthus multistachys on epithelial-mesenchymal transition via down-regulation of Runx2 activation in human breast cancer." dans: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 22, Issue 1, pp. 165-72, (2015) (PubMed).

Wang, Cai, Ma, Liu, Ke, Lu, Fu: "The natural compound codonolactone impairs tumor induced angiogenesis by downregulating BMP signaling in endothelial cells." dans: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 22, Issue 11, pp. 1017-26, (2015) (PubMed).

Fu, Ke, Tan, Liu, Wang, Ma, Lu: "The natural compound codonolactone attenuates TGF-?1-mediated epithelial-to-mesenchymal transition and motility of breast cancer cells." dans: Oncology reports, (2015) (PubMed).

Wang, Chen, Zou, Tu, Tan, Lu, Liu, Fu: "Codonolactone, a sesquiterpene lactone isolated from Chloranthus henryi Hemsl, inhibits breast cancer cell invasion, migration and metastasis by downregulating the transcriptional activity of Runx2." dans: International journal of oncology, Vol. 45, Issue 5, pp. 1891-900, (2014) (PubMed).

Tsimbouri, Murawski, Hamilton, Herzyk, Oreffo, Gadegaard, Dalby: "A genomics approach in determining nanotopographical effects on MSC phenotype." dans: Biomaterials, Vol. 34, Issue 9, pp. 2177-84, (2013) (PubMed).

Tsimbouri, McMurray, Burgess, Alakpa, Reynolds, Murawski, Kingham, Oreffo, Gadegaard, Dalby: "Using nanotopography and metabolomics to identify biochemical effectors of multipotency." dans: ACS nano, Vol. 6, Issue 11, pp. 10239-49, (2012) (PubMed).

McNamara, Sjöström, Burgess, Kim, Liu, Gordonov, Moghe, Meek, Oreffo, Su, Dalby: "Skeletal stem cell physiology on functionally distinct titania nanotopographies." dans: Biomaterials, Vol. 32, Issue 30, pp. 7403-10, (2011) (PubMed).

Tetsunaga, Nishida, Furumatsu, Naruse, Hirohata, Yoshida, Saito, Ozaki: "Regulation of mechanical stress-induced MMP-13 and ADAMTS-5 expression by RUNX-2 transcriptional factor in SW1353 chondrocyte-like cells." dans: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 19, Issue 2, pp. 222-32, (2011) (PubMed).

Détails sur RUNX2

Antigène: RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

Autre désignation: RUNX2 (RUNX2 Produits)

Synonymes: anticorps AML3, anticorps CBF-alpha-1, anticorps CBFA1, anticorps CCD, anticorps CCD1, anticorps CLCD, anticorps OSF-2, anticorps OSF2, anticorps PEA2aA, anticorps PEBP2aA, anticorps Cbf, anticorps Cbfa-1, anticorps Cbfa1, anticorps LS3, anticorps Osf2, anticorps Pebp2a1, anticorps Pebpa2a, anticorps runx2, anticorps RUNX2, anticorps ccd, anticorps aml3, anticorps ccd1, anticorps osf2, anticorps cbfa1, anticorps pea2aa, anticorps pebp2a1, anticorps pebp2a2, anticorps pebp2aa, anticorps pebp2aa1, anticorps runt related transcription factor 2, anticorps runt-related transcription factor 2a, anticorps runt-related transcription factor 2, anticorps runt related transcription factor 2 L homeolog, anticorps RUNX2, anticorps runx2a, anticorps Runx2, anticorps runx2, anticorps LOC703331, anticorps LOC100549663, anticorps runx2.L

Sujet: Synonyms: Runt-related transcription factor 2, Core-binding factor subunit alpha-1, CBF-alpha-1, Acute myeloid leukemia 3 protein, Oncogene AML-3, Polyomavirus enhancer-binding protein 2 alpha A subunit, PEBP2-alpha A, PEA2-alpha A, SL3-3 enhancer factor 1 alpha A

Poids moléculaire: 56648 DA

ID gène: 860

UniProt: Q13950