CD24 anticorps (N-Term)

N° du produit ABIN652728

Cet anticorps anti-CD24 est un anticorps Lapin Polyclonal détectant CD24 dans FACS, WB et IHC (p). Adapté pour Humain.

Aperçu rapide pour CD24 anticorps (N-Term) (ABIN652728)

Antigène: CD24 (CD24 Molecule (CD24))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD24 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB23639

Détail du produit anti-CD24 anticorps

Épitope: AA 1-30, N-Term

Homologie: Mouse (Murine)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CD24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human CD24.

Isotype: Ig Fraction

Information d'application

Indications d'application: Suggested dilutions:
WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Date de péremption: 6 months

Détails sur CD24

Antigène: CD24 (CD24 Molecule (CD24))

Autre désignation: CD24

Sujet: Function:
Modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells.

Cellular Location:
Cell membrane, Lipid-anchor, GPI-anchor.

Tissue Location:
B-cells. Expressed in a number of B-cell lines including P32/ISH and Namalwa. Expressed in erythroleukemia cell and small cell lung carcinoma cell lines. Also expressed on the surface of T-cells

Synonyms: CD_antigen=CD24, Flags: Precursor, Small cell lung carcinoma cluster 4 antigen, Signal transducer CD24, CD24, CD24A

Poids moléculaire: 8097 Da

ID gène: 100133941

NCBI Accession: NP_037362

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation