Cet anticorps anti-Protease Polyclonal Lapin (ABIN284976) détecte spécifiquement Protease dans ELISA et WB.
L’anticorps est réactif avec des échantillons de Human Immunodeficiency Virus (HIV).
Reactivité: Rat
ELISA, WB, IHC, IF/ICC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
ELISA: 1:500-1:1,000, WB: 1:500-1:1,000 Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Format
Frozen
Concentration
Lot specific
Buffer
Supplied frozen in PBS.
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Stock
4 °C/-20 °C
Stockage commentaire
Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -70 °C for long term storage.
Antigène
Protease
Classe de substances
Viral Protein
Sujet
HIV-1 protease (HIV PR) is a retroviral aspartyl protease that is essential for the life-cycle of HIV, the retrovirus that causes AIDS. HIV PR cleaves newly synthesized polyproteins at the appropriate places to create the mature protein components of an infectious HIV virion. Without effective HIV PR, HIV virions remain uninfectious. Thus, mutation of HIV PR’s active site or inhibition of its activity disrupts HIV’s ability to replicate and infect additional cells, making HIV PR inhibition the subject of much pharmaceutical research.