CD300a anticorps (FITC)

N° du produit ABIN2853603

L’anticorps Rat Monoclonal anti-CD300a a été validé pour FACS. Il convient pour détecter CD300a dans des échantillons de Souris.

Aperçu rapide pour CD300a anticorps (FITC) (ABIN2853603)

Antigène: CD300a (CD300A)

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD300a est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Clone: TX40

Détail du produit anti-CD300a anticorps (FITC)

Specificité: This antibody reacts with mouse CD300a antigen.

Purification: Mouse MAIR-I transfected Ba/F3 cells

Immunogène: Mouse MAIR-I transfected Ba/F3 cells

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS, 0.09 % NaN3, 1 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8 °C.

Détails sur CD300a

Antigène: CD300a (CD300A)

Autre désignation: CD300A / CMRF35H

Sujet: Immune responses are regulated by opposing positive and negative signals triggered by the interaction of activating and inhibitory cell surface receptors with their ligands. Shibuya et al. identified novel paired activated and inhibitory immunoglobulin-like receptors, designated myeloid-associated immunoglobulin-like receptor (MAIR) I and MAIR-II, whose extracellular domains are highly conserved by each other. MAIR-I, expressed on the majority of myeloid cells, including macrophages, granulocytes, mast cells, and dendritic cells, contains the tyrosine-based sorting motif and the immunoreceptor tyrosine-based inhibitory motif-like sequences in the cytoplasmic domains. On the other hand, MAIR-II, expressed on subsets of peritoneal macrophages and B cells, associates with the immunoreceptor tyrosine-based activation motif-bearing adaptor DAP12. MAIR-I is also known as CD300a/ CMRF-35-like Ig-like molecule-8 (CLM-8)/leukocyte mono-Ig-like receptor 1 (LMIR1). MAIR-II is also known as CD300d/LMIR2/CLM-4/dendritic cell-derived Ig-like receptor 1 (DIgR1).Synonyms: CD300 antigen-like family member A, CLM-8, CMRF-35-H9, CMRF35-H, CMRF35-H9, CMRF35-like molecule 8, IRC1/IRC2, IRp60, Inhibitory receptor protein 60, NK inhibitory receptor

ID gène: 217303

NCBI Accession: NP_739564

UniProt: Q6SJQ0

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process