CD52 anticorps (FITC)

N° du produit ABIN2853609

Détail du produit anti-CD52 anticorps (FITC)

Antigène: CD52

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD52 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Specificité: This antibody reacts with mouse CD52/CAMPATH-1.

Purification: Protein G agarose

Immunogène: Mouse IL-2Ralpha-transgenic mouse splenocyte

Clone: BTG-2G

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 1 % BSA and 0.09 % NaN3

Stock: 4 °C

Stockage commentaire: Store at 2-8 °C.

Détails sur CD52

Antigène: CD52

Autre désignation: CD52 / CAMPATH-1 (CD52 Produits)

Synonymes: anticorps CD52, anticorps AI463198, anticorps B7, anticorps B7-Ag, anticorps CAMPATH-1, anticorps CLS1, anticorps MB7, anticorps CDW52, anticorps CE5, anticorps CD52 molecule, anticorps CD52 antigen, anticorps CD52, anticorps Cd52

Sujet: CAMPATH-1, also known as CD52, is a heavily glycosylated, GP I-anchored protein expressed at high levels on almost all thymocytes, lymphocytes, monocytes, and macrophages. CAMPATH-1 is an exceptionally good target for complement-mediated cell lysis and antibody-mediated cellular cytotoxicity. Humanized CAMPATH-1 antibodies have been used therapeutically to effectively deplete lymphocytes in allogeneic bone marrow transplants, hematologic malignancies, and autoimmune diseases. Clinical trials suggest CAMPATH-1 antibodies are especially promising in the treatment of leukemia, non-Hodgkin lymphomas, and rh eumatoid arth ritis. The apparent size of CAMPATH-1 by SDS-PAGE is 25-29 kDa, however, the actual molecule is much smaller, ~ 8-9 kDa as confirmed by total structure analysis and mass spectrometry.Synonyms: CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, HE5

ID gène: 23833

NCBI Accession: NP_038734

UniProt: Q64389