CD52 anticorps (PE)

N° du produit ABIN2853610

Cet anticorps Rat Monoclonal détecte spécifiquement CD52 dans FACS. Il présente une réactivité envers Souris.

Aperçu rapide pour CD52 anticorps (PE) (ABIN2853610)

Antigène: CD52

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD52 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: BTG-2G

Détail du produit anti-CD52 anticorps (PE)

Specificité: This antibody reacts with mouse CD52 antigen.

Purification: Protein G agarose

Immunogène: IL-2Ralpha-transgenic mouse splenocyte

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: 50 tests in 1 mL volume of PBS containing 1 % BSA and 0.09 % NaN3

Stock: 4 °C

Stockage commentaire: Store at 2-8 °C.

Détails sur CD52

Antigène: CD52

Autre désignation: CD52 / CAMPATH-1

Sujet: CAMPATH-1, also known as CD52, is a heavily glycosylated, GPI-anchored protein expressed at high levels on almost all thymocytes, lymphocytes, monocytes, and macrophages. CAMPATH-1 is an exceptionally good target for complement-mediated cell lysis and antibody-mediated cellular cytotoxicity. Humanized CAMPATH-1 antibodies have been used therapeutically to effectively deplete lymphocytes in allogeneic bone marrow transplants, hematologic malignancies, and autoimmune diseases. Clinical trials suggest CAMPATH-1 antibodies are especially promising in the treatment of leukemia, non-Hodgkin lymphomas, and rh eumatoid arthritis. The apparent size of CAMPATH-1 by SDS-PAGE is 25-29 kDa, however, the actual molecule is much smaller, ~ 8-9 kDa as confirmed by total structure analysis and mass spectrometry.Synonyms: CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, HE5

ID gène: 23833

NCBI Accession: NP_038734

UniProt: Q64389