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CD52 anticorps (PE)

CD52 Reactivité: Souris FACS Hôte: Rat Monoclonal BTG-2G PE
N° du produit ABIN2853610
  • Antigène Voir toutes CD52 Anticorps
    CD52
    Reactivité
    • 62
    • 11
    • 7
    • 5
    • 4
    • 1
    Souris
    Hôte
    • 25
    • 19
    • 19
    • 1
    • 1
    Rat
    Clonalité
    • 48
    • 11
    • 3
    Monoclonal
    Conjugué
    • 33
    • 9
    • 7
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD52 est conjugé à/à la PE
    Application
    • 50
    • 20
    • 19
    • 16
    • 14
    • 13
    • 12
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    Flow Cytometry (FACS)
    Specificité
    This antibody reacts with mouse CD52 antigen.
    Purification
    Protein G agarose
    Immunogène
    IL-2Ralpha-transgenic mouse splenocyte
    Clone
    BTG-2G
    Isotype
    IgG2a
    Top Product
    Discover our top product CD52 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    50 tests in 1 mL volume of PBS containing 1 % BSA and 0.09 % NaN3
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8 °C.
  • Antigène
    CD52
    Autre désignation
    CD52 / CAMPATH-1 (CD52 Produits)
    Sujet
    CAMPATH-1, also known as CD52, is a heavily glycosylated, GPI-anchored protein expressed at high levels on almost all thymocytes, lymphocytes, monocytes, and macrophages. CAMPATH-1 is an exceptionally good target for complement-mediated cell lysis and antibody-mediated cellular cytotoxicity. Humanized CAMPATH-1 antibodies have been used therapeutically to effectively deplete lymphocytes in allogeneic bone marrow transplants, hematologic malignancies, and autoimmune diseases. Clinical trials suggest CAMPATH-1 antibodies are especially promising in the treatment of leukemia, non-Hodgkin lymphomas, and rh eumatoid arthritis. The apparent size of CAMPATH-1 by SDS-PAGE is 25-29 kDa, however, the actual molecule is much smaller, ~ 8-9 kDa as confirmed by total structure analysis and mass spectrometry.Synonyms: CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, HE5
    ID gène
    23833
    NCBI Accession
    NP_038734
    UniProt
    Q64389
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