NQO1 anticorps (Center)
Aperçu rapide pour NQO1 anticorps (Center) (ABIN2854319)
Antigène
Voir toutes NQO1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Center
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Réactivité croisée
- Souris, Porc, Rat (Rattus)
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Réactivité croisée (Details)
- Mouse (86 %), Pig (89 %), Rat (85 %)
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Attributs du produit
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Rabbit polyclonal antibody to NQO1 (NAD(P)H dehydrogenase, quinone 1)
NQO1 antibody [N1C3] -
Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human NQO1. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
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Commentaires
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Positive Control: 293T , A431 , HeLa , HepG2 , Molt-4 , Raji
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- 1XPBS, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))
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Autre désignation
- NQO1
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Sujet
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This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Cellular Localization: Cytoplasm -
Poids moléculaire
- 31 kDa
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ID gène
- 1728
Antigène
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